So on DTaP vaccination did you know.
Because of the small number of antigens (3-5 in DTaP vaccines vs >3000 in DTwP vaccines), linked-epitope suppression occurs. Because of linked-epitope suppression, all children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes, and there is no easy way to decrease this increased lifetime susceptibility.
Read that again.
All children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes.
Read the research paper here:
https://pubmed.ncbi.nlm.nih.gov/30793754/
So on DTaP vaccination did you know. Because of the small number of antigens (3-5 in DTaP vaccines vs >3000 in DTwP vaccines), linked-epitope suppression occurs. Because of linked-epitope suppression, all children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes, and there is no easy way to decrease this increased lifetime susceptibility. Read that again. All children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes. Read the research paper here: https://pubmed.ncbi.nlm.nih.gov/30793754/
PUBMED.NCBI.NLM.NIH.GOV
The 112-Year Odyssey of Pertussis and Pertussis Vaccines-Mistakes Made and Implications for the Future - PubMed
Effective diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines became available in the 1930s, and they were put into routine use in the United States in the 1940s. Their use reduced the average rate of reported pertussis cases from 157 in 100 000 in the prevaccine era to
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